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周志强

发布者:周志强 [发表时间]:2019-03-20 [来源]:威尼斯官网威尼斯官网 [浏览次数]:

周志强

学历、职称:博士、助理研究员/硕士生导师(分析化学、无机化学)

研究方向

(1) 纳米材料的可控制备

(2) 纳米生物传感器

(3) 纳米生物效应

联系方式:zhouzhiqiang814@sina.com

教育与研究经历

2012.9-2017.7 武汉大学物理化学专业,获理学博士学位

2017.7-至今 威尼斯官网(中国)股份有限公司助理研究员。

主要从事纳米材料的可控制备和性能研究、纳米生物传感器及纳米材料的生物效应研究工作,相关研究结果发表在NanoscaleSensors & Actuators B: ChemicalAnalytica Chimica ActaChemosphereRSC Advances等国际著名期刊。主持和参与国家级、省部级科研项目8项。

学情况

主讲本科生专业必修课《分析化学》和《分析化学实验》;指导本科生获国家级老员工创新创业计划项目1项、自治区级老员工创新创业计划项目3;指导本科生获广西高校化学化工类论文及设计竞赛二等奖2项、三等奖1项。

承担项目与课题

主持的科研项目:

  1. 广西自然科学基金青年基金,2018GXNSFBA138030,基于量子点掺杂机制的重金属离子探针的合成及应用,10万元,已结题、主持。

  2. 广西科技基地与人才专项,桂科AD20159068,线粒体靶向的活性氧荧光纳米探针的构建及其肿瘤细胞成像应用研究,10万元,在研、主持。

  3. [来源]:威尼斯官网博士科研启动项目,0819-2017L14,重金属离子荧光纳米探针的构建及应用,18万元,在研、主持。

  4. 污染物分析与资源化技术湖北重点实验室开放基金,一种基于掺杂机制的重金属元素检测的量子点探针,2万元,已结题、主持。

    参与的科研项目:

  5. 国家自然科学基金面上项目,21473125,低毒近红外发光量子点与蛋白质相互作用的热力学基础,已结题、参与。

  6. 国家杰出青年科学基金项,21225313,生物热化学,已结题、参与。

  7. 国家自然科学基金面上项目,21673166,具有线粒体靶向抗肿瘤功能的有机胂化合物的生物活性及其作用机制热力学基础研究,在研、参与。

  8. 国家自然科学基金项目,基于靶向近红外碳量子点纳米生物传感器的构筑及其超高灵敏识别病毒核酸的应用基础研究,在研、参与。

  9. 广西自然科学基金项目,2018JJA110055,阻氚涂层中氢/氦与晶体缺陷的交互作用行为及涂层长期服役可靠性研究,在研、参与。

主要学术论文

  1. Zhi-Qiang Zhou, Li-Yun Yang*, Ling Huang, Yuan-Ping Liao, Yi Liu, Qi Xiao*. A novel fluorescent probe for H2O2 detection based on CdSe@ZnS quantum dots/Ag nanocluster hybrid, Analytica Chimica Acta, 2020, 1106, 176-182. (中科院大类二区,IF=6.558

  2. Zhi-Qiang Zhou, Yuan-Ping Liao, Jing Yang, Shan Huang, Qi Xiao, Li-Yun Yang*, Yi Liu*. Rapid ratiometric detection of Cd2+ based on the formation of ZnSe/CdS quantum dots, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 228: 117795. (中科院大类二区,IF=4.098

  3. Zhi-Qiang Zhou, Li-Yun Yang*, Yuan-Ping Liao, Hui-Yan Wu, Xiao-Hui Zhou, Shan Huang, Yi Liu, Qi Xiao*. Mn:ZnSe quantum dots-based turn-on fluorescent sensor for highly selective and sensitive detection of Cd2+, Analytical Methods, 2020, 12, 552-556. (中科院大类三区,IF=2.896

  4. Zhi-Qiang Zhou, Ren Yan, Jie Zhao, Li-Yun Yang, Ji-Lei Cheng, Feng-Lei Jiang*, Yi Liu*. Highly selective and sensitive detection of Hg2+ based on fluorescence enhancement of Mn-doped ZnSe QDs by Hg2+-Mn2+ replacement, Sensors & Actuators B: Chemical, 2018, 254: 8-15. (中科院大类一区,IF=7.46

  5. Zhi-Qiang Zhou, Li-Yun Yang, Ren Yan, Jie Zhao, Yu-Qi Liu, Lu Lai, Feng-Lei Jiang*, Thomas Maskow*, Yi Liu*. Mn-Doped ZnSe quantum dots initiated mild and rapid cation exchange for tailoring the composition and optical properties of colloid nanocrystals: novel template, new applications. Nanoscale, 2017, 9(8): 2824-2835. (中科院大类一区,IF=7.796

  6. Li-Yun Yang, Si-Yu Hua, Jun-Peng Fan, Zhi-Qiang Zhou, Guan-Chao Wang, Feng-Lei Jiang, Zhi-Xiong Xie, Qi Xiao, Yi Liu*. Inhibition of autophagy via lysosomal impairment enhances cytotoxicity of fullerenol under starvation condition. ACS Applied Bio Materials, 2020, 3(2): 977-985.

  7. Shan Huang, Hai-Mei Li, Hua-Jian Luo, Li-Yun Yang, Zhi-Qiang Zhou, Qi Xiao*, Yi Liu*. Conformational structure variation of human serum albumin after binding interaction with black phosphorus quantum dots, International Journal of Biological Macromolecules, 2020, 146: 405-414.

  8. Xu Chu, Gan Ning, Zhi-Qiang Zhou, Yi Liu, Qi Xiao*, Shan Huang. Bright Mn-doped carbon dots for the determination of permanganate and L-ascorbic acid by a fluorescence on-off-on strategy, Microchimica Acta, 2020, 187(12): 1-11.

  9. Shan Huang, Jian-Dong Yao, Xu Chu, Gan Ning, Zhi-Qiang Zhou, Yi Liu, Qi Xiao*. A ratiometric fluorescent assay for evaluation of alkaline phosphatase activity based on ionic liquid-functionalized carbon dots, Microchimica Acta, 2020, 187(5): 1-10.

  10. Qing Tian, Lu Lai*, Zhi-Qiang Zhou, Ping Mei, Qing-Ye Lu, Yan-Qun Wang, Dong Xiang, Yi Liu. The interaction mechanism of different surfactants with casein: a perspective on bulk and interfacial phase behavior, Journal of Agricultural and Food Chemistry, 2019, 67: 6336-6349.

  11. Ren Yan, Bing-Qiong Yu, Miao-Miao Yin, Zhi-Qiang Zhou, Xun Xiang, Xiao-Le Han, Yi Liu and Feng-Lei Jiang*. The interactions of CdTe quantum dots with serum albumin and subsequent cytotoxicity: the influence of homologous ligands, Toxicology research, 2018, 7(2): 147-155.

  12. Qi-Xiang Mei, Lu Lai* , Zhi-Qiang Zhou, Ping Mei, Zhao-Hua Ren, Yan-Cheng Zheng, Yi Liu. Impact of multiple quaternary ammonium salts on dynamic properties of BSA adsorption layer at different pH values. Soft Matter, 2017, 13(40): 7273-7282.

  13. Li-Yun Yang, Si-Yu Hua, Zhi-Qiang Zhou, Guan-Chao Wang, Feng-Lei Jiang, Yi Liu*. Characterization of fullerenol-protein interactions and an extended investigation on cytotoxicity. Colloids & Surfaces B: Biointerfaces, 2017, 157:261.

  14. Jian-Cheng Jin, Zi-Qiang Xu, Han-Feng Zou, Zhi-Qiang Zhou, Qi-Qi Yang, Bei-Bei Wang, Feng-Lei Jiang, Yi Liu*. Carbon dots reduced and stabilized silver nanoclusters: synthesis and formation mechanisms. RSC Advances, 2016, 6(80), 76989-76995.

  15. Jie Zhao, Zhi-Qiang Zhou, Jian-Cheng Jin, Lian Yuan, Huan He, Feng-Lei Jiang*, Xiao-Gang Yang*, Jie Dai, Yi Liu. Mitochondrial dysfunction induced by different concentrations of gadolinium ion. Chemosphere, 2014, 100, 194-199.

  16. Jie Zhao, Jian-Cheng Jin, Zhi-Qiang Zhou, Cai-Fen Xia, Xiao-Gang Yang*, Feng-Lei Jiang, Jie Dai, Yi Liu*. High concentration of gadolinium ion modifying isolated rice mitochondrial biogenesis. Biological Trace Element Research, 2013, 156(1-3), 308-315.

    发明专利

  17. 刘义;周志强; 蒋风雷; 杨立云; 刘雨奇。一种水溶性过渡金属掺杂ZnSe量子点的合成方法,发明专利,中国,已授权,专利授权号:ZL201510966336.8

  18. 刘义;周志强; 杨立云; 颜稔; 陈纪磊; 蒋风雷。基于掺杂离子发光机制的汞离子探针及其合成方法与应用,发明专利,中国,已授权,专利授权号:ZL201610965341.1

  19. 周志强;杨立云;黄凌;刘义。复合荧光纳米探针的制备及其对过氧化氢的检测方法,发明专利,中国,已公布,CN 110835528A

  20. 周志强;廖远萍;杨立云;刘义。11-巯基十一烷酸修饰的金纳米簇的制备方法及其应用,发明专利,中国,已公布,CN 110981896A

  21. 周志强;岑建芳;杨立云;杨美金。特异性检测Ag+CdSe量子点的制备及其检测方法和应用,发明专利,中国,已公布,CN 111795958A

  22. 周志强;廖远萍;杨立云;杨美金;刘义。ZIF-8包覆的金纳米簇材料及其制备方法和应用,发明专利,中国,已公布,CN 111961462A